MS observational study

Analyzing key factors for multiple sclerosis (MS) disease severity and progression to support individualized care

What is the MS observational study?

In a collaborative effort with Biogen and Brigham and Women’s Hospital, we conducted a study to decipher why multiple sclerosis (MS) progresses so differently among diagnosed individuals, and to glean insights that may inform new therapies and improve care for MS patients.

How are you making it happen?

Our program built on the Brigham and Women’s Hospital's Comprehensive Longitudinal Investigation of MS (CLIMB) Study. Through new collaborative studies, our teams worked to identify various factors that correlate with MS disease severity and progression. One study analyzed clinical, radiological and biological data collected from MS patients to identify the main factors associated with the severity and progression of the disease. Another study tested the feasibility of the investigational Verily Study Watch in measuring the mobility, gait and dexterity of MS patients. 

The studies combined wearable sensors with traditional clinical and lab-based tests designed to gather and analyze biological, physiological, behavioral and environmental variables. With this data, our software team used machine learning algorithms and other computational techniques to generate deeper insights. This research represents another step towards uncovering potential new treatment possibilities and supporting individualized care for MS. See our findings published in Nature.